abstract：AIMS:The aim of the current study was to developed and test the reliability of a technique for measuring temporal parameters of sucking in breastfeeding infants. METHODS:The technique was developed using a cohort of 11 term and 12 preterm infants, and subsequently evaluated using a cohort of 43 preterm infants. Measur...

journal_title：Early human development

authors： Rocha AD,Lopes JM,Ramos JR,Gomes SC Jr,Lopes Lucena S,Medeiros A,Lopes Moreira ME

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:Controversy exists regarding association of high levels of proinflammatory cytokines, neonatal morbidities and poor neurodevelopment outcome in very low birth weight infants. OBJECTIVE:To determine association between severity of early inflammatory response and neurodevelopment outcome in high risk very low...

journal_title：Early human development

authors： Silveira RC,Procianoy RS

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:Placental pathology is associated with long-term neurological morbidity. Little is known about the association of placental pathology and illness severity directly after birth in preterm infants. OBJECTIVE:To determine the association between placental pathology and illness severity in preterm infants durin...

journal_title：Early human development

authors： Roescher AM,Hitzert MM,Timmer A,Verhagen EA,Erwich JJ,Bos AF

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:Higher parenting stress in mothers of children born very preterm may be in part a response to poorer neurobehavioral development, reflecting realistic concerns in addition to adaptation to the trauma of preterm delivery. To our knowledge, there are few longitudinal studies of parenting stress that have addre...

journal_title：Early human development

authors： Brummelte S,Grunau RE,Synnes AR,Whitfield MF,Petrie-Thomas J

更新日期：2011-04-01 00:00:00

abstract：:Neonatal hyperglycaemia is a frequent complication in VLBW infants during the first week of life. The more common causes include high glucose intake, stress situations such as sepsis, NEC, and surgical treatments, as well as the administration of vasoactive drugs and methylxanthines. The appropriate definition is uncl...

journal_title：Early human development

authors： Decaro MH,Vain NE

更新日期：2011-03-01 00:00:00

abstract：:Fungal-related morbidity and mortality is a major concern for most neonatal intensive care units (NICUs) worldwide. Incidence rates are increasing and might be higher than reported due to the challenges associated with diagnosing fungal infections. As preterm neonates display clinical characteristics that make them pr...

journal_title：Early human development

authors： Manzoni P,Jacqz-Aigrain E,Rizzollo S,Franco C,Stronati M,Mostert M,Farina D

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:cardiac arrhythmias are commonly observed in the fetus, however, may have major consequences for fetal development and post natal life. AIMS:to evaluate the perinatal management and cardiac outcome of fetuses with tachy- or bradyarrhythmia. STUDY DESIGN:perinatal management, outcome and long-term cardiac f...

journal_title：Early human development

authors： Hahurij ND,Blom NA,Lopriore E,Aziz MI,Nagel HT,Rozendaal L,Vandenbussche FP

更新日期：2011-02-01 00:00:00

abstract：AIM:the effect of selective head cooling on cerebral blood flow (CBF) and cerebral metabolism rate (CMR) was investigated in newborn piglets. METHODS:seven days old newborn piglets were randomly assigned to one of the following three groups: Selective head cooling in normal piglets (n=4), selective head cooling after ...

journal_title：Early human development

authors： Cheng G,Sun J,Wang L,Shao X,Zhou W

更新日期：2011-02-01 00:00:00

abstract：:Newborn infants, especially preterm infants, have an immature immune system, which is not capable to actively protect against vaccine-preventable infections. Therefore, the newborn is dependent on transplacental transport of Immunoglobulin G (IgG), an active, FcRn receptor mediated process. Fetal IgG rises from approx...

journal_title：Early human development

authors： van den Berg JP,Westerbeek EA,van der Klis FR,Berbers GA,van Elburg RM

更新日期：2011-02-01 00:00:00

abstract：:Case-control studies are frequently performed in prenatal and perinatal epidemiology. For data collection, these studies often rely on self-administered questionnaires or personal interviews. Although of importance, validation of these measurement instruments received little attention in epidemiologic research so far....

journal_title：Early human development

authors： van Gelder MM,Roeleveld N

更新日期：2011-01-01 00:00:00

abstract：:Intrauterine growth restriction (IUGR) is associated with altered lung development in human and rat. The transcription factor PPARγ, is thought to contribute to lung development. PPARγ is activated by docosahexanoic acid (DHA). One contribution of PPARγ to lung development may be its direct regulation of chromatin mod...

journal_title：Early human development

authors： Joss-Moore LA,Wang Y,Baack ML,Yao J,Norris AW,Yu X,Callaway CW,McKnight RA,Albertine KH,Lane RH

更新日期：2010-12-01 00:00:00

abstract：:Vascular tumours (haemangiomas and malformations) are common tumours of infancy and childhood. They represent a group of mostly benign conditions, which present early, can grow rapidly and be symptomatic or disfiguring. There are various management options, with different cosmetic and functional outcomes. Haemangiomas...

journal_title：Early human development

authors： McHoney M

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND:Parent perception of child vulnerability (PPCV) and parent overprotection (POP) are believed to have serious implications for age appropriate cognitive and psychosocial development in very low birth weight preterm children. AIM:With recent concerns about suboptimal developmental outcomes in late-preterm chi...

journal_title：Early human development

authors： Samra HA,McGrath JM,Wey H

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:Children with major anatomical congenital anomalies (CA) often need prolonged hospitalization with surgical interventions in the neonatal period and thereafter. Better intensive care treatment has reduced mortality rates, but at the cost of more morbidity. AIM:To study motor-function and exercise capacity i...

journal_title：Early human development

authors： van der Cammen-van Zijp MH,Gischler SJ,Mazer P,van Dijk M,Tibboel D,Ijsselstijn H

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND:Patent ductus arteriosus (PDA) is a frequent problem in preterm infants, and its incidence is inversely correlated with gestational age. The efficacy of medical treatment decreases with decreasing gestational age (GA), and failure rates as well as ductus ligation rates of 40% have been reported in <28 week G...

journal_title：Early human development

authors： Pees C,Walch E,Obladen M,Koehne P

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND:Children born preterm are known to be at risk for neurodevelopmental disorders. The role of perinatal asphyxia in this increased risk is still a matter of debate. AIM:To analyze the contribution of perinatal asphyxia in a population of preterm infants admitted to a secondary paediatric setting to neurologic...

journal_title：Early human development

authors： van Iersel PA,Bakker SC,Jonker AJ,Hadders-Algra M

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:The requirement of essential fatty acids (EFA) for the development of the brain is well documented. OBJECTIVE:To investigate the early neurological development at term and 44 weeks gestational age in preterm infants in relation to EFA concentrations in breast milk and in infants' and mothers' plasma phospho...

journal_title：Early human development

authors： Lundqvist-Persson C,Lau G,Nordin P,Strandvik B,Sabel KG

更新日期：2010-07-01 00:00:00

abstract：:Nutrition has a key role in the modulation of the developing intestine in early infancy, and nutrients are able to modulate several intestinal functions including nutrient absorption, ion transport, cell growth and differentiation, motility and immunomodulation. Such modulation is exerted in part through a direct inte...

journal_title：Early human development

authors： Buccigrossi V,Giannattasio A,Armellino C,Lo Vecchio A,Caiazzo MA,Guarino A

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:In severe intrauterine growth restriction (IUGR) due to placental insufficiency a haemodynamic adaptation occurs, resulting in preferential blood flow to the fetal brain (brain sparing). With Doppler ultrasound an increased ratio between the umbilical and the cerebral artery pulsatility index (U/C ratio) can...

journal_title：Early human development

authors： van den Broek AJ,Kok JH,Houtzager BA,Scherjon SA

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:Fetal cells exfoliate in the uterine cavity during early pregnancy and are a potential source of material for NIPD. AIMS:This study was designed to test the hypothesis that fetal cells obtained from the uterine cervix during the first trimester of pregnancy could be utilized for prenatal diagnosis of chromo...

journal_title：Early human development

authors： Sifakis S,Ghatpande S,Seppo A,Kilpatrick MW,Tafas T,Tsipouras P,Fejgin M,Amiel A

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:Previous studies using ultrasound technology showed that fetal heart rate (HR) may be responsive to maternal aerobic exercise. Although it is recognized that cardiac autonomic control may be influenced by the intrauterine environment, little is known about how maternal exercise affects fetal heart developmen...

journal_title：Early human development

authors： May LE,Glaros A,Yeh HW,Clapp JF 3rd,Gustafson KM

更新日期：2010-04-01 00:00:00

abstract：OBJECTIVE:To evaluate the pregnancy outcome in pregnancies with threatened abortion (miscarriage). MATERIAL AND METHOD:A prospective cohort study was performed on 1000 pregnant women. 500 women (case group), had a history of vaginal bleeding during the first half of pregnancy and the other 500 women (control group), d...

journal_title：Early human development

authors： Dadkhah F,Kashanian M,Eliasi G

更新日期：2010-03-01 00:00:00

abstract：:Among 7 subjects with hyperemesis gravidarum (HG), we found gabapentin therapy to be associated with mean reductions in nausea and emesis from Baseline to Days 12-14 of 80% and 94%, respectively. There have been 2 congenital defects among 7 exposed infants. Gabapentin may be effective in the treatment of HG. ...

journal_title：Early human development

authors： Guttuso T Jr,Robinson LK,Amankwah KS

更新日期：2010-01-01 00:00:00

abstract：AIM:The effects of intestinal bifidobacteria on the development of immunity in early life were explored. METHODS:Neonatal SD rats born and housed under strict barrier systems were fed from birth with sufficient antibiotics (bifidobacteria minimisation group) or supplemented daily with 1x10(10) colony-forming units of ...

journal_title：Early human development

authors： Dong P,Yang Y,Wang WP

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:A reliable and valid assessing tool to detect the problem before the child becomes deviant is very important. AIM:This study aimed to further test the reliability and validity of developmental screening instrument for follow-up of thirty-six months children in Taiwan. Also, the stability and changes in the ...

journal_title：Early human development

authors： Lung FW,Chiang TL,Lin SJ,Lee MC,Shu BC

更新日期：2010-01-01 00:00:00

abstract：:The introduction of exchange transfusion made it possible to prevent severe hyperbilirubinemia and kernicterus, but kernicterus has never completely disappeared and it is still occurring in North America and, more frequently in Western Europe and the developing world. I discuss the epidemiology and major causes of sev...

journal_title：Early human development

authors： Maisels MJ

更新日期：2009-11-01 00:00:00

abstract：:Newborn infants fulfil some criteria of being conscious i.e. being aware of the body, the self and the world. They are able to differentiate between self and nonself touch, express emotions and show signs of shared feelings. They process sensory impressions including pain at a cortical level. They remember rhythmic so...

journal_title：Early human development

authors： Lagercrantz H

更新日期：2009-10-01 00:00:00

abstract：:Low nephron endowment secondary to intrauterine growth restriction (IUGR) results in compensatory hypertrophy of the remaining glomeruli, which in turn is associated with hypertension. However, gender differences exist in the response of the kidney to injury, and IUGR female offspring seems protected from an unfavorab...

journal_title：Early human development

authors： Baserga M,Bares AL,Hale MA,Callaway CW,McKnight RA,Lane PH,Lane RH

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND:Cases suggestive of non-acidemia related cerebral palsy (CP) are likely misdiagnosed as acidemia related CP because of the presence of nonreasuring fetal heart rate (FHR) patterns. AIMS:Our purpose was to compare intrapartum FHR patterns between the cases of neurological damage and the cases without disabil...

journal_title：Early human development

authors： Kodama Y,Sameshima H,Ikeda T,Ikenoue T

更新日期：2009-04-01 00:00:00

abstract：OBJECTIVE:To establish longitudinal reference ranges for the fetal superior mesenteric artery (SMA) flow velocity and pulsatility index (PI(SMA)). Also to examine the hemodynamic relationship to venous liver perfusion and umbilical flow distribution in the liver, to other splanchnic arteries, and more generally to the ...

journal_title：Early human development

authors： Ebbing C,Rasmussen S,Godfrey KM,Hanson MA,Kiserud T

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND:Some researchers have developed child feeding indices to summarize child feeding practices so that they can compare child feeding practices across countries and monitor changes over time within a given country. AIMS:An adapted version of the infant and child feeding index (ICFI) developed by Ruel and Menon ...

journal_title：Early human development

authors： Zhang J,Shi L,Wang J,Wang Y

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND:Among preterm infants, high concentrations of inflammatory mediators in cerebrospinal fluid (CSF) are associated with poor outcome. Previous studies have not indicated whether CSF concentrations of inflammatory mediators are associated with important confounders such as gestational age. AIMS:To examine asso...

journal_title：Early human development

authors： Turner MA,Drury JA,Carlin A,O'Neill S,Pilling D,Barnes N,Balmer P,Newland P,Clark S,Kissack CM,Subhedar NV

更新日期：2009-04-01 00:00:00

abstract：OBJECTIVE:To identify obstetric risk factors and to elucidate the effect of prolonged rupture of the membranes on the development of cystic periventricular leukomalacia (PVL) in preterm infants. METHODS:A retrospective case-control study of 95 preterm infants with the diagnosis of PVL and 245 healthy controls matched ...

journal_title：Early human development

authors： Bauer M,Fast C,Haas J,Resch B,Lang U,Pertl B

更新日期：2009-03-01 00:00:00

abstract：:Magnetic Resonance Imaging is becoming more widely available and increasingly important for imaging the neonatal brain. In newborn infants it poses challenges regarding patient preparation, safety, optimal timing, and sequence optimization. These issues are addressed in this paper and indications for performing neonat...

journal_title：Early human development

authors： van Wezel-Meijler G,Leijser LM,de Bruïne FT,Steggerda SJ,van der Grond J,Walther FJ

更新日期：2009-02-01 00:00:00

abstract：:White matter injury and abnormal maturation are thought to be major contributors to the neurodevelopmental disabilities observed in children and adolescents who were born preterm. Early detection of abnormal white matter maturation is important in the design of preventive, protective, and rehabilitative strategies for...

journal_title：Early human development

authors： Dudink J,Kerr JL,Paterson K,Counsell SJ

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND:Pregnant women's sleep disturbance due to fetal movement is well known. Fetal movement is thought to be an index of fetal well-being. However, as there has never been a way to easily and reliably record fetal movement, psychophysiological studies of pregnant women's sleep disturbance and fetal well-being hav...

journal_title：Early human development

authors： Nishihara K,Horiuchi S,Eto H,Honda M

更新日期：2008-09-01 00:00:00

abstract：:The diagnosis, acute management and follow-up of neonates with haemolytic disease of the newborn (HDN) still represents a significant area of activity for maternity/neonatal services. ABO incompatability is now the single largest cause of HDN in the western world. However, with increasing knowledge at the molecular le...

journal_title：Early human development

authors： Roberts IA

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:Previous studies have reported an increased incidence of thyroid dysfunction in premature/low birth weight infants. The cord blood concentrations of transthyretin (TTR), a thyroid hormone binding protein, have also been found to be decreased in preterm infants. While thyroid hormone concentrations are decrea...

journal_title：Early human development

authors： Su PH,Wang SL,Chen JY,Hu JM,Chang HP,Chen SJ

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:There is concern that exposure of preterm infants to noxious insults over a prolonged period may have long term effects on their developing nervous system. AIMS:To investigate medium and long term effects of heel pricks in infants over the first year of life. STUDY DESIGN:Study 1-a longitudinal study, 2 da...

journal_title：Early human development

authors： Abdulkader HM,Freer Y,Garry EM,Fleetwood-Walker SM,McIntosh N

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND:Few studies describe in detail the pregnancy and early development of infants with Prader-Willi syndrome (PWS). However, variations at these early stages may partially account for differences in the later phenotype. A recent paper described an abnormally high number of problems in pregnancy and early infancy...

journal_title：Early human development

authors： Whittington JE,Butler JV,Holland AJ

更新日期：2008-05-01 00:00:00